RPRM and gastric cancer: These genes are involved in crucial tumorigenic processes such as cell cycle regulation (p16NK4a, p15INK4b, p14ARF, RPRM, RUNX3), apoptosis (XIAP, BCL2, DAPK, BNIP3, TMS1, CASP8, GPX3, RNF180), DNA repair (hMLH1, MSH2, MGMT), migration, and invasion (CDH1, CDH4, PCDH10, RASSF1A, ZIC1, APC, GRIK2, FLNC, LOX, TIMP3, TSP1), among others, and have been associated with the progression and poor prognosis of GC [7,8].