Expression of miRNA-124 was also found significantly reduced in patients with active lupus nephritis (LN) compared with patients with non-active LN and was negatively correlated with the mRNA expression in the serum of interleukins (IL) 1β and 6, tumor necrosis factor-alpha (TNF-α), and TNF receptor associated factor-6 (TRAF6) [44]. The gene discussed is TRAF6; the disease is lobular neoplasia.