HDAC6 and ovarian carcinoma: However, among the cell lines tested in this study (Figure 2D and Figure S1A), all cells expressed high levels of HDAC6 and the metastatic ovarian carcinoma cell line, SMG 5 and SMG 19, demonstrated very strong HDAC6 expression, which also correlated with greater cell proliferation compared with the low HDAC6 expressing SMG 6 and 35 cells (Figure 2E).