PTPN13 and ovarian serous carcinoma: These results were confirmed by Wang et al. in a high-grade serous ovarian carcinoma (HGSOC) cell line (OV-90), in which PTPN13 transfection decreased the levels of IκBα phosphorylated at Y42 and of nuclear NF-κB, in contrast to transfection with PTPN13 siRNA.