SRC [38], ephrinB [40], EGFR [67], and HER2 [37,38] signaling are inhibited by PTPN13 that limits anchorage-independent cell growth (SRC) [49], cell proliferation (HER2 and EGFR) [67], and also invasion and tumor aggressiveness (SRC, HER2) [37,38]. This evidence concerns the gene PTPN13 and neoplasm.