Amyotrophic lateral sclerosis (LAS): In 2016, Bonafede et al. [157] showed that exosomes derived from the murine adipose-derived stromal cell are able to protect NSC-34 cells (which overexpress human SOD1(G93A) or SOD1(G37R) or SOD1(A4V) mutants) from oxidative damage, which is responsible for ALS-related damages. Here, SOD1 is linked to amyotrophic lateral sclerosis.