The analysis of relationships between calcification indicators and markers of endothelial dysfunction in the atherosclerotic foci revealed direct moderate correlations between osteopontin and sVCAM-1 (r = 0.388, p = 0.001) and MCP-1 (r = 0.523, p = 0.0001) and between osteonectin and sVCAM-1 (r = 0.669, p = 0.0001), MCP-1 (r = 0.421, p = 0.0001), and E-selectin (r = 0.520, p = 0.001). This evidence concerns the gene SPP1 and endothelial dysfunction.