We found that glyceraldehyde-3-phosphate dehydrogenase, enolase, triosephosphate isomerase, 14-3-3 protein, and fructose-1,6-bisphosphate aldolase [109,110,111,112,113,114,115,116] elicited IgG antibodies during PCM. Here, GAPDH is linked to paracoccidioidomycosis.