Our findings contrast those of Evans et al. who reported black women had a greater expression of several inflammatory genes isolated from adipose tissue compared to white women [28]; however, despite this, the inflammatory profile of black women only explained 20% of their variation in insulin sensitivity compared to 56% in white women, suggesting that the greater risk of T2D in black women may not be mediated by adipose tissue inflammation. This evidence concerns the gene INS and type 2 diabetes mellitus.