IL17A and infection: IL-17A produced mainly by Th17 cells during secondary infections could play a relevant role during the “cytokine storm” that arises during an aberrant and uncontrolled immune response to dengue infection and participates in a synergistic mechanism with other pro-inflammatory cytokines to amplify systemic inflammation, which together suggest that Th17 and other IL-17-producing cells can play key roles in the immunopathogenesis of dengue infection.