Dengue patients showed elevated serum levels for IL-17A (median 76.0 pg/mL, IQR 24.6–121.4), IL-17F (median 10.5 pg/mL, IQR 2.1–34.9), IL-22 (median 29.3 pg/mL, IQR 0–89.8) and IL-23 (median 14.7 pg/mL, IQR 6.2–31.0) compared to HC (IL-17A, median 0 pg/mL, IQR 0–33.5; IL-17F, median 5.2 pg/mL, IQR 1.1–14.5; IL-22, median 5.2 pg/mL, IQR 0–31.2; and IL-23, median 0 pg/mL, IQR 0–13.1). This evidence concerns the gene IL17A and dengue disease.