The objectives of this study were to determine the frequency of CD4+IL-17-producing cells and the levels of related cytokines (IL-17A, IL-17F, IL-22, and IL-23) in dengue patients relative to healthy controls (HC), as well as, how these levels are affected in primary and secondary infections and related to the severity of infection (DF and DHF). The gene discussed is IL22; the disease is dengue disease.