Furthermore, IL-1β has been demonstrated to induce the expression and the release of IL-17 in γδ T cells (γδ T cells are a small subset of T cells that express heterodimeric T cell receptors composed of γ and δ chains) that led to the expansion and polarization of granulocyte-colony stimulating factor (G-CSF)-dependent neutrophils in mammary tumor-bearing mice. This evidence concerns the gene CSF3 and breast cancer.