Aykut et al. (2019) [67] also provided evidence that the population of Malassezia present in the digestive tract may be correlated with the development of other non-cutaneous pathologies, as representatives of this genus seem to compose a significant part of the microorganisms that invade the pancreatic duct, from the intestinal lumen, contributing to the development of ductal pancreatic adenocarcinoma (PDA), through activation of the complement cascade, via interaction with mannan-binding lectins (MBLs) [68]. Here, MBL2 is linked to Patent ductus arteriosus.