Intensively, a study by Christopher et al. (2020) indicated that the IFN suppression of SARS-CoV-2 (probably through NSP3 on IRF3) effectively curated inflammatory responses through the cGAS-STING pathway, correlating to immunopathies from IFN dysregulation, which is worsen in severe COVID-19 [37,38,39]. The gene discussed is CGAS; the disease is COVID-19.