Although no analytical alteration is pathognomonic of ACLI, there are some findings that suggests its diagnosis [5]: (1) an alanine aminotransferase (ALT)-to-LDH ratio <1.5 is of great help in the differential diagnosis, as it is rarely seen in other etiologies of hepatitis [70]; (2) the aspartate aminotransferase (AST) generally peaks earlier and higher than ALT [68]. This evidence concerns the gene GPT and hepatitis A virus infection.