TLR2 and gastric cancer: A TLR2-dependent gene signature associated with increased cell growth and poor overall survival has been identified in human gastric cancer, corresponding to the up-regulation of six anti-apoptotic genes (BCL2A1, BCL2, BIRC3, CFLAR, IER3, TNFAIP3) and the down-regulation of the tumor suppressors PDCD4 and TP53INP1 [57].