Multiple allergens are involved in WA [142]: sera from patients with baker’s asthma and rhinitis react with amylase inhibitors, germ agglutinin, peroxidase and non-specific lipid transfer proteins (LTPs) [143]; WDEIA is induced by ω5-gliadins [144]; IgE from patients with atopic dermatitis, urticaria and anaphylaxis are reactive with α, β, γ, ω-gliadins, and low and high molecular weight subunits. This evidence concerns the gene IGHE and urticaria.