APOE and cardiovascular disorder: Compared with those not included in the analytical sample 2, the included participants in midlife were younger (p < 0.001), more likely to be female (p = 0.031), more educated (p < 0.001), had higher proportions of ideal smoking (p = 0.002), ideal BMI (p = 0.004), and ideal blood pressure (p < 0.001), a higher score of global, behavioral, and biological CVH metrics (all p < 0.001), and were less likely to carry APOE ε4 allele (p = 0.003) and have cardiovascular diseases (p = 0.024).