AVP and Hyperinsulinemia: Although the caloric intake remained high in the HFCS-HWI group (Figure 3C), there was a remarkable lowering of serum copeptin (Figure 3D) in association with lower body weight (Figure 3E), fatty liver (Figure 3, F–H), hyperinsulinemia and hyperleptinemia (Figure 3, I and J), adipocyte inflammatory changes (Figure 3K), and fat mass and percentage (Figure 3, L and M).