We have recently demonstrated that the differentially expressed genes in the developing neocortex of Satb2 mutants are enriched for genes with human orthologues associated with schizophrenia (SZ) and educational attainment (EA) and for genes harboring de novo variants reported in autism spectrum disorder (ASD) and intellectual disability (ID) (Whitton et al, 2018). The gene discussed is SATB2; the disease is schizophrenia.