ROBO4 and lung cancer: Similarly, for full protein–protein interaction involving variants within the non-interacting regions of the proteins; 3 variants of ROBO1, 2 variants of SLIT2 and 2 variants of ROBO4 from lung cancer dataset and 3 variants of ROBO1, 3 variants of SLIT2, and 2 variants of ROBO4 were prioritised for further docking and post-docking analyses.