HIF1A and diabetes mellitus: These repressed levels of miR-210 reflect the impaired HIF-1 signaling in diabetic wounds1 since they could be reversed when HIF-1 signaling was restored by local treatment with Dimethyloxalylglycine (DMOG) known to be able to overcome the repressing effect of diabetes on HIF-1 signaling2 (Fig. 2e, f).