SQSTM1 and neoplasm: For instance, twist is degraded by both the autophagy and proteasome pathways.37 Snail was found to be degraded naturally through autophagy in a different model.41–43 Vimentin has been identified to be ligated to the autophagy adapter protein p62, which is presumably associated with autophagy pathways.44 However, its misfolded body is degraded by the proteasome system.45 FN1 in the cytoplasm of tumour cells is called oncofoetal fibronectin (OncFN).