Local (IgA) and systemic (IgG) antibodies recognizing several pertussis-specific virulence factors, including FHA, an autotransporter (Vag8), Bordetella resistance to killing (BrkA), and fimbria 2/3 (Fim2/3), were induced after vaccination, but anti-PT antibodies were not observed (15). This evidence concerns the gene F2 and pertussis.