TLR2 and pertussis: A recent preclinical mucosal vaccination study using a novel adjuvant LP-GMP (a combination of an intracellular receptor stimulator of interferon gene [STING] agonist and a ligand of Toll-like receptor 2 [TLR2]) combined with an acellular vaccine as well as an additional study using outer membrane vesicles (OMVs) of pertussis vaccine (omvPV) demonstrated that i.n. immunization with a pertussis vaccine can confer protection from B. pertussis challenge (14, 15).