Of the genes misregulated in Mir183/96dko homozygotes, five are known deafness genes; Myo3a, Slc26a5 and Tmc1 underlie deafness in mice and humans (Kurima et al., 2002; Liberman et al., 2002; Liu et al., 2003; Vreugde et al., 2002; Walsh et al., 2002, 2011), while mutations in Sema3e cause deafness in people (Lalani et al., 2004), and mice lacking Ocm exhibit progressive hearing loss (Tong et al., 2016). Here, SEMA3E is linked to deafness.