In non-small cell lung carcinoma (NSCLC), RET fusion with 5′-UTRs have been described for at least twelve partner genes, i.e. KIF5B, CCDC6, NCOA4, MYO5C, EPFA5, TRIM33, CLIP1, ERC1, PICALM, FRMD4A, RUFY2 and TRIM24 (Ferrara et al., 2018). The gene discussed is CCDC6; the disease is non-small cell lung carcinoma.