In non-small cell lung carcinoma (NSCLC), RET fusion with 5′-UTRs have been described for at least twelve partner genes, i.e. KIF5B, CCDC6, NCOA4, MYO5C, EPFA5, TRIM33, CLIP1, ERC1, PICALM, FRMD4A, RUFY2 and TRIM24 (Ferrara et al., 2018). This evidence concerns the gene PICALM and non-small cell lung carcinoma.