Alterations in MYC signaling are hallmarks of many human cancers, such as small cell lung cancer and Burkitt lymphoma (Dalla-Favera et al., 1982; Kim et al., 2016), and alterations in the MYC pathway have been observed in ∼30% of cancers with diverse histologies (Schaub et al., 2018). The gene discussed is MYC; the disease is small cell lung carcinoma.