The CCL2-mediated basophil chemotactic activity of anaphylactic serum and the reduction in circulating basophils during anaphylaxis, coupled with the previous finding that basophils are the granulocytes most resistant to apoptosis [41], suggest that anaphylaxis induces rapid CCL2-mediated basophil migration rather than elimination by apoptosis. The gene discussed is CCL2; the disease is anaphylaxis.