In the present study, while CDAA-HF-T(+) and CDAA-HF-T(−) equally caused the accumulation of hepatic lipid content, inflammatory and fibrotic changes (represented by F4/80 and α-SMA scores, respectively) were only slightly increased in the CDAA-HF-T(−) group than in the CDAA-HF-T(+) group at the end of week 13. The gene discussed is ACTA1; the disease is hydrops fetalis.