Moreover, preclinical study showed synergistic activity between the BCL-2 inhibitor navitoclax (ABT-263) and bendamustine [104], but the phase II clinical study on navitoclax plus bendamustine and rituximab in r/r DLBCL was withdrawn due to non-safety-related reasons (NCT01423539). Here, BCL2 is linked to diffuse large B-cell lymphoma.