Though ITAM (immunoreceptor tyrosine-based activation motif) mutation of CD79b was frequently recognized in 23% of ABC r/r DLBCL [62], the reported activities of polatuzumab vedotin showed no preference for any DLBCL cell-of-origin subtypes or CD79b expression [64, 65]. This evidence concerns the gene CD79B and aneurysmal bone cyst.