The data showed that the expression of E-cadherin was impaired, while the expression of N-cadherin and Vimentin was elevated in cells containing NSCLC serum-derived exosomes (Fig. 2i, j), suggesting that NSCLC serum-derived exosomes induced A549 and H460 cell migration and invasion. The gene discussed is VIM; the disease is non-small cell lung carcinoma.