Natriuretic peptides—b-type natriuretic peptide (BNP) and N terminal pro BNP (NTproBNP)—and cardiac troponins (Tn) I and T are found to be elevated in HF following increased myocardial wall stress, elevated filling pressures, subendocardial ischemia etc. [3,4]. The gene discussed is NPPB; the disease is hydrops fetalis.