On the other hand, the data from the Korean cohort study for the outcome in patients with chronic kidney disease (KNOW-CKD) study, a large cross-sectional study of pre-dialysis CKD patients, showed that fibroblast growth factor 23 (FGF-23) was associated with coronary artery calcification only in the high serum adiponectin group [93]. The gene discussed is ADIPOQ; the disease is chronic kidney disease.