There may be many reasons for the lack of consensus on Lamin A/C effects on prostate cancer and other cancer’s, such as tumors showing heterogeneous lamin A/C expression, lamin A/C’s many roles in the cell and in cancer progression, and the fact that lamin A and lamin C expression levels can change independently of one another [70,71,72,81,82,111]. This evidence concerns the gene LMNA and Familial prostate cancer.