NAT10 and Hutchinson-Gilford progeria syndrome: The molecule remodlin restores nuclear shape in Hutchinson–Gilford progeria syndrome (HGPS) cells, which contain a mutated form of lamin A/C called progerin, as remodlin inhibits N-acetyltransferase 10 (NAT10), which is linked with SUN1 and plays a role in anchoring microtubules [35].