In a recent study, Deng et al. have demonstrated that the long non-coding RNA LNC00461, a sponge for miR-15a/16, was highly expressed in MM exosomes and enhanced MM cell proliferation by relieving the inhibitory effect of (miR)-15a/miR-16 on the anti-apoptotic protein BCL-2. This evidence concerns the gene BCL2 and Miyoshi myopathy.