Seven (16%) were immunosuppressed, including three patients with hematological malignances (acute myeloid leukemia, smoldering multiple myeloma, and chronic myeloid leukemia), two patients with autoimmune disease (with history of anti-tumor necrosis factor treatment but no active treatment during CPI), one with history of kidney transplant (receiving everolimus and prednisone), and one with recently diagnosed, active tuberculosis receiving rifamycin/isoniazid/pyrazinamide/ethambutol treatment. The gene discussed is TNF; the disease is autoimmune disease.