Our results also suggest that overall there is no difference in physiological folate levels based on MTHFR C677T genotype (Table 1), but at times there may be higher physiological folate levels in those with TT genotypes (Tables 3 and 4), despite previous research suggesting that individuals who are TT homozygous would be more prone to folate deficiency [60]. This evidence concerns the gene MTHFR and folate deficiency.