CCND1 and lung carcinoma: On the other hand, the over-expression of PGM5P4-AS1 significantly inhibited the expression of CyclinD1 (0.37±0.05 vs. 0.93±0.09), MMP-2 (0.41±0.07 vs. 1.22±0.17), Bcl-2 (0.30±0.05 vs. 1.05±0.14), and Bcl-xl (0.37±0.06 vs. 0.91±0.11) in lung cancer cells (Figure 5(f)).