Among various inflammatory blood biomarkers, CRP and IL‐6 were two most studied in the literatures (Matsuo et al., 2016; VanGilder et al., 2014; Whiteley et al., 2009), some of which report conflicting results and this may reflect the complex physiology of CRP or IL‐6 and true differences between stroke subtypes and populations (Bustamante et al., 2014; Yu et al., 2017). This evidence concerns the gene IL6 and stroke disorder.