Indeed, glutamine restriction induced apoptosis in Notch1‐positive T‐ALL cells (CUTLL1, HPB‐ALL, and MOLT4), but not in Notch1‐negative cells (H33HJ‐JA1 and LOUCY), as determined by the population of annexin V/PI‐positive cells (Figs 2D and S2a). This evidence concerns the gene ANXA5 and acute lymphoblastic leukemia.