Major Lamin A disruption occurs in Hutchinson‐Gilford progeria syndrome (HGPS), as a consequence of mutations in the gene encoding for this protein, that is, LMNA. HGPS is a rare genetic condition that leads to accelerated ageing and brain development abnormalities (Gonzalo et al., 2017), demonstrating the link between nuclear envelope integrity, ageing and neurodegeneration. Here, LMNA is linked to Hutchinson-Gilford progeria syndrome.