Recent research shows that HDAC3 is effective for the control of lung alveolar macrophage development and homeostasis, and further evidence indicates that the affected antigen‐presenting function of cluster 3 and the immune‐responsive function of cluster 4 are probably the consequences of loss of HDAC3, suggesting that HDAC3 may play a role in lung cancer.131. This evidence concerns the gene HDAC3 and lung carcinoma.