The ProMisE classification has several advantages, as it shows a higher concordance between preoperative endometrial biopsy and hysterectomy compared with tumor histotype and grade11, 12, is able to differentiate high‐grade tumors with excellent prognosis (POLE EDM) from tumors with poor prognosis (p53 abn)8, 9, 10, can evaluate tumors in the gray zone between endometrioid and serous histotype and can identify women with MMR‐D, who may have Lynch syndrome and who should be referred for genetic counseling and testing.8, 9, 10. This evidence concerns the gene TP53 and neoplasm.