ERVW-1 and hepatocellular carcinoma: For example, Xiong et al. [53] reported that after stimulated MCs with the hepatitis C virus E2 envelope glycoprotein, MC-derived exosomal miR-490 was highly expressed, and the miR-490 level in HCC cells was increased following coculture with exosomes derived from MCs, subsequently decreasing the migrating ability of HCC cells.