Another report showed that WNT3A increases the level of expression of programmed death-ligand 1 (PD-L1) on the surface of GBM cells, which is an important protein that inhibits the activation, expansion and effector functions of cells with antitumor activity (TCD8+) (54), corroborating the importance of WNT3A in immune evasion (55). Here, WNT3A is linked to glioblastoma.