For example, NAFLD patients significantly had higher circulating Hb concentration than healthy subjects.47 In some previous studies, higher values of RDW and PDW were also observed in NAFLD patients, compared to controls.17,18,48 Additionally, several independent studies have found that steatosis was associated with higher MPV.49,50 Based on our expansive search, there were no previous studies examining the effects of OEA on hematological factors. This evidence concerns the gene GSTM1 and metabolic dysfunction-associated steatotic liver disease.