In addition to positive dengue, our patient showed a positive COVID-19 PCR result ( RealStar® SARS-CoV-2 RT-PCR Kit 1.0, Altona Diagnostics, Hamburg, Germany) in the screening swab but had negative IgG and IgM using Liaison Sars-CoV-2 S1/S2 (DiaSorin, Saluggia, Italy) for COVID-19 in the sample done on day 12 post-symptoms. The gene discussed is CD40LG; the disease is dengue disease.