With regard to severity-specific findings, it is worth noting that Singh et al. [46] found an association for SNP rs17268974 in the STS gene with Type II hypospadias and for seven SNPs in the STS gene and two in the STARD3 gene with Type III hypospadias, genes involved in steroid metabolism, whereas, no association was found for Type I hypospadias for these SNPs. The gene discussed is STS; the disease is hypospadias.