Compared with the subjects without an APOE-ε4 allele, the TC level was significantly higher in those with any ε4 allele within the AD group (P < 0.05) (Table 4), and the TC and LDL levels were also higher in those with any ε4 allele within the NC group (P < 0.05) (Table 5). The gene discussed is APOE; the disease is Alzheimer disease.