IL4 and neoplasm: In order to characterize the M-406/CBi/L model with respect to cytokines involved in the different phases of tumor immunoediting, it was evaluated the concentration of Th-1 (IFN-γ, IL-2) and Th-2 (IL-10, IL-4) cytokines in serum from tumor bearing animals during EL, EQ and ES phases (Figure 2).