Circulating cDC1s from HBV patients displayed reduced expressions of DECTIN1 (Figure 1a), CLEC9A (Figure 1c) together with increased expression of FcɣRIIA (Figure 1c and Supplementary figure 2b) compared with HD, while intrahepatic cDC1s exhibited a reduced expression of DCIR (Figure 1a), CLEC9A, FcɣRIIA, (Figure 1c) and MMR (MFI) (Supplementary figure 2c) together with increased expression of DECTIN1 (Figure 1a) compared to controls. The gene discussed is CLEC7A; the disease is Huntington disease.