Despite the abnormalities reported so far, NK cells retain their ability to efficiently induce antibody-dependent cellular cytotoxicity (ADCC), through the binding of CD16 (FcγRIIIA) to the Fc-regions of antibody-antigen complexes located on the surface of tumor cells (31, 34, 41, 46, 53). This evidence concerns the gene FCGR3A and neoplasm.