described the case of a 19-year-old man with a peculiar MEN1 phenotype, characterized by a parathyroid adenoma, pancreatic islet cell tumors in association with two enlarged hepatic hilar lymph nodes that were not biopsied, and a non-functioning pituitary mass with supra- and parasellar invasion, harboring craniospinal and systemic metastases (96). This evidence concerns the gene MEN1 and parathyroid gland adenoma.